Gingrich J R, Paulson D F
Department of Surgery, Duke University Medical Center, Durham, North Carolina, USA.
Surg Oncol Clin N Am. 1995 Apr;4(2):335-44.
Despite a negative metastatic evaluation, up to 100% of patients with high-grade tumors are found to harbor metastatic disease within the pelvic lymph nodes at the time of surgery. This article reviews the literature regarding efforts to refine noninvasive preoperative staging through the use of serum tumor markers, improved radiologic imaging, and histologic analysis of the biopsy specimens. A discussion of the renewed controversy regarding the role of pelvic lymphadenectomy in the management of adenocarcinoma of the prostate follows.
尽管转移评估结果为阴性，但高达100%的高级别肿瘤患者在手术时被发现盆腔淋巴结存在转移性疾病。本文回顾了有关通过使用血清肿瘤标志物、改进的放射影像学检查以及活检标本的组织学分析来完善非侵入性术前分期的相关文献。随后讨论了盆腔淋巴结清扫术在前列腺腺癌治疗中作用的新争议。
