Stöver B, Laubenberger J, Niemeyer C, Stahl F, Brandis M, Langer M
Department of Paediatric Radiology, Humboldt University, Berlin, Germany.
Pediatr Radiol. 1995;25(2):123-6. doi: 10.1007/BF02010325.
MRI findings of 18 examinations of six children with haemangiomatosis and one with extended arteriovenous malformation are reported. Structures involved were the liver, liver and lung, periorbital area and the thigh. Response to interferon therapy, in particular, was assessed. With MRI the disease can be characterized and the extent of the lesions and size of the haemangiomas measured. Coronal views provide excellent demonstration of the involved structures in liver and lung haemangiomatosis. Two children showed response to interferon therapy with a reduction in lesion size and subsequently in number. Signal intensity decreased slightly on T2-weighted images. During treatment, however, no definitive fibrotic zones were seen. Following complete regression, signal intensity of the liver parenchyma was homogeneous in both weightings, that is, no fibrotic areas were visible 18 months after the beginning of treatment. Two children showed no response and one child died from congestive cardiac failure. The periorbital haemangioma was reduced in size and the lesion in the thigh might be classified as an arteriovenous malformation. In children MRI can replace CT as it is a reliable imaging modality for diagnosing haemangiomatosis and monitoring therapy.
报告了对6例患有血管瘤病的儿童和1例患有广泛性动静脉畸形的儿童进行的18次检查的MRI结果。受累结构包括肝脏、肝脏和肺、眶周区域及大腿。特别评估了对干扰素治疗的反应。通过MRI可对该疾病进行特征性描述，并测量病变范围和血管瘤大小。冠状位图像能很好地显示肝脏和肺部血管瘤病的受累结构。两名儿童对干扰素治疗有反应，病变大小随后减少，数量也减少。在T2加权图像上信号强度略有降低。然而，治疗期间未见到明确的纤维化区域。完全消退后，肝脏实质在两种加权图像上的信号强度均均匀，即在治疗开始18个月后未见纤维化区域。两名儿童无反应，一名儿童死于充血性心力衰竭。眶周血管瘤大小减小，大腿部病变可能归类为动静脉畸形。在儿童中，MRI可替代CT，因为它是诊断血管瘤病和监测治疗的可靠成像方式。
