Hsu C D, Smith K, Hong S F, Johnson T R, Gollin Y, Chan D W
Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Am J Perinatol. 1995 May;12(3):205-7. doi: 10.1055/s-2007-994453.
Since pathologic changes of the placenta have been found in preeclamptic pregnancies, a relationship between fetal-maternal hemorrhage and preeclampsia was investigated. Sixty-two women with singleton pregnancies in the third trimester were studied. Thirty-one of these women with preeclampsia were matched with 31 normotensive healthy pregnant women. Maternal serum levels of alpha-fetoprotein (MSAFP) and Kleihauer-Betke (KB) test were determined to reflect the degree of fetal-maternal hemorrhage. There were no significant differences in MSAFP levels, MSAFP to creatinine ratio, or the appearance of fetal cells as measured by the KB test between preeclamptic pregnancies and matched controls. Our data do not suggest that fetal-maternal hemorrhage is increased in pregnant women with preeclampsia.
由于在子痫前期妊娠中发现了胎盘的病理变化，因此对胎儿-母体出血与子痫前期之间的关系进行了研究。对62名单胎妊娠晚期妇女进行了研究。其中31名子痫前期妇女与31名血压正常的健康孕妇进行了匹配。测定母体血清甲胎蛋白（MSAFP）水平和克列豪尔-贝特克（KB）试验，以反映胎儿-母体出血的程度。子痫前期妊娠与匹配对照组之间的MSAFP水平、MSAFP与肌酐比值或通过KB试验测量的胎儿细胞出现情况均无显著差异。我们的数据并不表明子痫前期孕妇的胎儿-母体出血增加。
