Dorval T, Michon J, Tartour E, Fridman W H
Service de médecine oncologique, institut Curie, Paris, France.
Bull Cancer. 1995;82 Suppl 2:127s-138s.
Cancer immunotherapy has been carried out since the early fifties and first involved nonspecific system (BCG, Corynebacterium parvum, levamisole...). More recently, the production of cytokines as interferons or interleukin 2, the introduction of monoclonal antibodies have allowed a new development to cancer immunotherapy. Nevertheless, these new approaches have to be considered as a step in the biological therapy of cancer.
癌症免疫疗法自五十年代初就已开展,最初涉及非特异性系统(卡介苗、短小棒状杆菌、左旋咪唑……)。最近,诸如干扰素或白细胞介素2等细胞因子的产生以及单克隆抗体的引入,使癌症免疫疗法有了新的发展。然而,这些新方法必须被视为癌症生物治疗中的一个步骤。