Rózalska B
Zakład Biologii Infekcyjnej Instytutu Mikrobiologii i Immunologii Uniwersytetu Lódzkiego.
Postepy Hig Med Dosw. 1994;48(5):521-42.
The major proteins from plasma and extracellular matrices (ECM) are described. The interaction of lymphoid cells with their microenvironment is critical for their growth and function. The interaction with ECM may play a significant role in defining the biological properties of many cells. ECM form a network of bioactive proteins, that is being linked with an increasing number of processes, including antigen-independent activation, proliferation, homing and cell migration. Some aspects of the participation of the extracellular matrix in the language of intracellular communication is discussed.
文中描述了血浆和细胞外基质(ECM)中的主要蛋白质。淋巴细胞与其微环境的相互作用对其生长和功能至关重要。与细胞外基质的相互作用可能在决定许多细胞的生物学特性方面发挥重要作用。细胞外基质形成了一个生物活性蛋白网络,该网络与越来越多的过程相关联,包括抗原非依赖性激活、增殖、归巢和细胞迁移。本文讨论了细胞外基质参与细胞内通讯的一些方面。