Beckendorf V
Service de Radiothérapie, Centre Alexis Vautrin, Vandoeuvre-lès-Nancy.
Rev Mal Respir. 1995;12(3):203-18.
GOAL. To re-define the type and place of radiotherapy in non-small cell bronchial carcinoma, where the disease is localised, either operable or non-operable, and in metastatic disease. METHOD. A review of the literature, review of the principle randomised trials and non-randomised trials describing innovative procedures, and a commentary and debate. For operable disease the indications for post-operative radiotherapy are redefined and the treatments envisaged such as those proposed using new adjuvents which may or may not include radiotherapy are discussed. For non-operable disease, different possibilities have been explored, including increased doses of treatment, modifications of the fraction regime, the association of radio-chemotherapy either concomitantly or successively. In metastatic disease the place of mediastinal radiotherapy is discussed and the possibility of radiation of the metastatic sites is recalled.
目标。重新界定放射治疗在非小细胞支气管癌中的类型和应用场景，包括疾病局限、可手术或不可手术的情况以及转移性疾病。方法。对文献进行综述，回顾主要的随机试验和描述创新方法的非随机试验，并进行评论和讨论。对于可手术疾病，重新界定术后放疗的适应症，并讨论所设想的治疗方法，例如使用可能包括或不包括放疗的新辅助治疗方法。对于不可手术疾病，探索了不同的可能性，包括增加治疗剂量、改变分次方案、同步或序贯放化疗联合。对于转移性疾病，讨论纵隔放疗的应用场景，并提及对转移部位进行放疗的可能性。
