Köhler F, Romaniuk P, Witt C, Stockheim D, Mergenthaler H G, Grunewald R, Baumann G
Medizinische Klinik und Poliklinik I, Charité, Humboldt-Universität Berlin.
Dtsch Med Wochenschr. 1995 Aug 4;120(31-32):1074-9. doi: 10.1055/s-2008-1055447.
A 58-year-old man was hospitalized because of threatened asphyxia resulting from massive obstruction to neck vein flow and increased venous markings over the ventral and dorsal thorax. The previous year he had received radiotherapy (total of 55.8 Gy) for squamous cell carcinoma in the right upper lobe of the lung (primary stage T2 N2 M0). The signs of venous congestion had developed over several months.
Emergency phlebography demonstrated obstruction to superior vena cava (SVC) flow by tumour compression.
It was possible to pass the SVC obstruction with a hydrophilic guide-wire and then perform a balloon angioplasty, followed later by implantation of two intraluminal expandable stents ("Wallstent"). The dyspnoea quickly improved after the successful recanalization. The day after the intervention palliative radiotherapy of the SVC obstruction was begun. But increased venous markings over the thorax recurred, but without dyspnoea, after 4 1/2 months free of signs of venous congestion. Repeat phlebography again demonstrated complete obstruction of the SVC by the tumour. Recanalization by balloon angioplasty was again achieved.
This case underlines the value of percutaneous balloon angioplasty with stent implantation as supplementary treatment in the late stages of SVC obstruction by tumour.
一名58岁男性因颈部静脉血流严重受阻及胸腹前侧和后侧静脉压迹增加导致窒息风险而住院。前一年,他因右肺上叶鳞状细胞癌(原发灶T2 N2 M0)接受了放疗(总量55.8 Gy)。静脉充血迹象在数月内逐渐出现。
急诊静脉造影显示上腔静脉(SVC)血流因肿瘤压迫而受阻。
使用亲水导丝成功通过SVC阻塞部位,随后进行球囊血管成形术,之后植入了两枚腔内可扩张支架(“Wallstent”)。成功再通后呼吸困难迅速改善。干预后第二天开始对上腔静脉阻塞进行姑息性放疗。但在无静脉充血迹象的4个半月后,胸部静脉压迹再次出现,不过未伴有呼吸困难。再次静脉造影显示肿瘤再次完全阻塞上腔静脉。再次通过球囊血管成形术实现再通。
该病例强调了经皮球囊血管成形术联合支架植入作为肿瘤所致上腔静脉阻塞晚期辅助治疗的价值。