Spindle cell lipomas. A report of two cases: one with multiple lesions.

BACKGROUND

Spindle cell lipoma is an unusual and histologically distinctive form of lipoma occurring primarily in older individuals.

OBJECTIVE

The dermatologic surgeon and pathologist should be familiar with this variant of lipoma.

METHODS

We are reporting two cases of spindle cell lipomas with the results of histologic examination with special stains and immunohistochemical studies.

RESULTS

The neoplasms consisted of lobulated masses of mature adipose tissue with areas of spindle cell proliferation. There was strong positive staining with antibodies for vimentin within the areas of spindle cells proliferation. One of the cases is unusual in that multiple lesions are occurring in a young patient.

CONCLUSION

Recognition of the histologic pattern is important in distinguishing the benign spindle cell lipoma from the malignant liposarcoma.