Baliga M, Holmquist N, Warrier R P
Department of Pathology, University of Mississippi Medical Center, Jackson 39216, USA.
Diagn Cytopathol. 1995 Jun;12(4):357-9. doi: 10.1002/dc.2840120415.
Accurate staging as per National Wilms' Tumor Study (NWTS) criteria is essential for therapy of Wilms' tumor. We report a unique case of a 9-mo-old white male in whom the diagnosis based upon clinical, radiological, surgical, and initial histopathologic findings was Stage I Wilms' tumor without regard to a positive cytologic examination of a small amount (5 ml) of chylous ascitic fluid obtained intraoperatively. This problem was clarified later at the NWTS panel review when the deeper recuts of a renal hilar lymph node revealed a single cluster of Wilms' tumor cells in capsular sinus, resulting in upstaging of tumor to Stage III. The significance of these findings in relation to staging will be discussed.
根据国家肾母细胞瘤研究（NWTS）标准进行准确分期对于肾母细胞瘤的治疗至关重要。我们报告了一例独特病例，一名9个月大的白人男性，根据临床、放射学、手术及初始组织病理学检查结果诊断为Ⅰ期肾母细胞瘤，术中获取的少量（5毫升）乳糜腹水细胞学检查呈阳性未被考虑在内。后来在NWTS小组审查时，对肾门淋巴结进行更深层次切片检查发现包膜窦中有单个肾母细胞瘤细胞簇，从而将肿瘤分期提升至Ⅲ期，这一问题得以明确。将讨论这些发现对于分期的意义。
