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肾上腺素能激动剂对豚鼠回肠末端纵行和环行平滑肌作用的分析。

Analysis of the effect of adrenergic agonists on longitudinal and circular smooth muscle of the terminal ileum of the guinea pig.

作者信息

Minker E, Kádár T, Bartha C

出版信息

Acta Physiol Acad Sci Hung. 1978;52(4):449-54.

PMID:754502
Abstract

On the isolated longitudinal smooth muscle of the guinea pig's terminal ileum, in the presence of naphazoline, synephrine, pholedrine and ephedrine showing no adrenergic agonist activity, the dose-response curves of adrenaline and noradrenaline was found to be shifted to the right. Metanephrine, normetanephrine, and 3-methoxy-4-hydroxyphenylethylamine exhibited no alpha adrenergic agonist activity. On the circular smooth muscle of the terminal ileum the alpha adrenergic agonists studied elicited the same responses as on the longitudinal smooth muscle.

摘要

在豚鼠回肠末端的离体纵行平滑肌上,在萘甲唑啉、辛弗林、去甲对羟福林和麻黄碱无肾上腺素能激动剂活性的情况下,发现肾上腺素和去甲肾上腺素的剂量-反应曲线向右移动。变肾上腺素、去甲变肾上腺素和3-甲氧基-4-羟基苯乙胺无α肾上腺素能激动剂活性。在回肠末端的环形平滑肌上,所研究的α肾上腺素能激动剂引起的反应与在纵行平滑肌上相同。

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Analysis of the effect of adrenergic agonists on longitudinal and circular smooth muscle of the terminal ileum of the guinea pig.肾上腺素能激动剂对豚鼠回肠末端纵行和环行平滑肌作用的分析。
Acta Physiol Acad Sci Hung. 1978;52(4):449-54.
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