Danchaivijitr S, Chokloikaew S, Trakoolsomboon S, Tangtrakool T
Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 1995 Jul;78 Suppl 1:S40-3.
A study on the contamination of antiseptics was done in a teaching hospital, during March and April 1989. Ninety-five samples of 9 antiseptics from 23 wards were cultured. Results showed that 2 of 12 and 3 of 5 samples of mercurochrome and chlorhexidine-cetrimide compound were contaminated. This led to a wider scale study on the two products. It was found that over one-half of the samples of mercurochrome and 6 of 54 samples of chlorhexidine-etrimide compound were contaminated. Mercurochrome was contaminated by gram-positive and chlorhexidine-cetrimide compound by gram-negative bacteria. Contamination of mercurochrome was found in samples taken from the pharmacy and wards, and of chlorhexidine-cetrimide compound from wards only. Mercurochrome was removed from the hospital formulary and the use of chlorhexidine-cetrimide compound was more restricted.
1989年3月至4月期间，在一家教学医院开展了一项关于防腐剂污染情况的研究。对来自23个病房的9种防腐剂的95个样本进行了培养。结果显示，红汞的12个样本中有2个、洗必泰-溴化十六烷基三甲铵复方的5个样本中有3个被污染。这促使对这两种产品进行更广泛的研究。结果发现，超过一半的红汞样本以及洗必泰-溴化十六烷基三甲铵复方的54个样本中有6个被污染。红汞被革兰氏阳性菌污染，洗必泰-溴化十六烷基三甲铵复方被革兰氏阴性菌污染。在从药房和病房采集的样本中发现了红汞的污染情况，而洗必泰-溴化十六烷基三甲铵复方的污染仅在病房样本中被发现。红汞从医院处方中被移除，洗必泰-溴化十六烷基三甲铵复方的使用也受到了更多限制。
