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评估水胶体/藻酸盐敷料对全层压疮的临床疗效。

Assessing clinical efficacy of a hydrocolloid/alginate dressing on full-thickness pressure ulcers.

作者信息

Barr J E, Day A L, Weaver V A, Taler G M

出版信息

Ostomy Wound Manage. 1995 Apr;41(3):28-30, 32, 34-6 passim.

PMID:7546113
Abstract

An absorbent hydrocolloid/alginate spiral dressing and a hydrocolloid secondary dressing were used in the management of 30 patients with 30 exuding State III and IV pressure ulcers. After a mean treatment time of 12.9 days (SD 6.5), all wounds had a significant increase in the amount of granulation tissue/epithelium and a decrease in the amount of devitalized tissue (p < 0.05). Wounds that underwent wide surgical debridement prior to the study were covered with 15 percent fibrin slough at study entry versus 39 percent for non-debrided wounds (p < 0.05). The dressing combination facilitated wound contraction and removal of fibrin slough in ulcers that were surgically debrided prior to the study. Ulcers which had not been surgically debrided expanded as autolytic debridement reduced the amount of fibrin slough/necrotic tissue present at the wound bed (Mean: 17.6 percent, p < 0.05). The absorbent spiral dressing helped manage exudate, was easy to use and comfortable for the patients. The average time between dressing changes in these exuding wounds was 1.56 days (SD = 0.95). Use of air-fluidized bed or mattress was found to significantly reduce wear time of the dressing (p < 0.01). Further studies are needed to confirm short-term, and evaluate long-term effects of this dressing combination on healing and debridement.

摘要

一种吸水性水胶体/藻酸盐螺旋敷料和一种水胶体二级敷料用于治疗30例患有30处有渗出的Ⅲ期和Ⅳ期压疮的患者。平均治疗时间为12.9天(标准差6.5)后,所有伤口的肉芽组织/上皮组织量显著增加,失活组织量减少(p<0.05)。在研究前接受广泛手术清创的伤口在研究开始时15%覆盖有纤维蛋白痂,而未清创的伤口为39%(p<0.05)。这种敷料组合促进了研究前接受手术清创的溃疡的伤口收缩和纤维蛋白痂的清除。未接受手术清创的溃疡随着自溶性清创减少了伤口床处的纤维蛋白痂/坏死组织量而扩大(平均值:17.6%,p<0.05)。吸水性螺旋敷料有助于处理渗出液,使用方便且患者感觉舒适。这些有渗出伤口的换药间隔平均时间为1.56天(标准差=0.95)。发现使用气悬浮床或床垫可显著缩短敷料的使用时间(p<0.01)。需要进一步研究来证实这种敷料组合对愈合和清创的短期效果,并评估其长期效果。

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Clin Microbiol Rev. 2001 Apr;14(2):244-69. doi: 10.1128/CMR.14.2.244-269.2001.