淋巴细胞发育与功能过程中的生与死：两种不同杀伤机制的证据
Life and death during lymphocyte development and function: evidence for two distinct killing mechanisms.
作者信息
Strasser A
机构信息
Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia.
出版信息
Curr Opin Immunol. 1995 Apr;7(2):228-34. doi: 10.1016/0952-7915(95)80007-7.
PMID:7546382
Abstract
During their development and after their functional activation most lymphocytes die, either because they fail to receive a survival signal or because they are actively killed. Recent experiments on Bcl-2 and Fas/Apo-1 have provided evidence that these two death processes are subject to distinct genetic control.
摘要
在其发育过程中以及功能激活后，大多数淋巴细胞会死亡，要么是因为它们未能接收到存活信号，要么是因为它们被主动杀死。最近关于Bcl-2和Fas/Apo-1的实验提供了证据，表明这两个死亡过程受到不同的基因控制。
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