Hett D A, Smith D C, Pilkington S N, Abbott T R
Shackleton Department of Anaesthesia, Southampton General Hospital.
Br J Anaesth. 1995 Sep;75(3):293-6. doi: 10.1093/bja/75.3.293.
We have recorded auditory evoked potentials before and during cardiopulmonary bypass in 10 adult patients undergoing cardiac surgery under moderate hypothermia to 27-28 degrees C. The immediate effect of bypass was a small decrease in latency and increase in amplitude of the early cortical response. We also studied two adults and two children during profound hypothermia with circulatory arrest during cardiopulmonary bypass. Reduction in core temperature to 25 degrees C resulted in an increase in latency and amplitude of the brain stem responses; below this temperature the amplitude decreased but latency continued to increase until the auditory evoked response trace became completely flat between 21 and 19 degrees C. These changes were reversible on rewarming.
我们记录了10例在中度低温（27 - 28摄氏度）下接受心脏手术的成年患者在体外循环前和体外循环期间的听觉诱发电位。体外循环的即刻效应是早期皮层反应的潜伏期略有缩短，波幅增大。我们还研究了2例成年人和2例儿童在体外循环期间深度低温并循环停止的情况。核心体温降至25摄氏度导致脑干反应的潜伏期延长和波幅增大；低于此温度时波幅减小，但潜伏期继续延长，直到听觉诱发电位在21至19摄氏度之间完全消失。这些变化在复温后是可逆的。
