Venge P
Asthma Research Centre, University of Uppsala, University Hospital, Sweden.
Pediatr Pulmonol Suppl. 1995;11:34-5. doi: 10.1002/ppul.1950191119.
The serum levels of eosinophil cationic protein (ECP) are raised in asthmatic children and indicate an eosinophil involving inflammatory process of the lungs. ECP measurements in serum may be used to monitor the severity of asthma in children and the efficacy of treatment with inhaled corticosteroids as well as to monitor allergen exposure. From these rather indirect studies we suspect that the inflammatory process in childhood asthma is the same as that seen in adults and involves the eosinophils.
哮喘儿童的血清嗜酸性粒细胞阳离子蛋白（ECP）水平升高，这表明嗜酸性粒细胞参与了肺部的炎症过程。测定血清中的ECP可用于监测儿童哮喘的严重程度、吸入性皮质类固醇的治疗效果以及监测过敏原暴露情况。从这些相当间接的研究中我们推测，儿童哮喘的炎症过程与成人相同，且涉及嗜酸性粒细胞。
