Rowlings P A, Passweg J R, Armitage J O, Gale R P, Sobocinski K A, Klein J P, Zhang M J, Horowitz M M
IBMTR and ABMTR Statistical Center, Medical College of Wisconsin, Milwaukee, USA.
Clin Transpl. 1994:87-98.
Bone marrow transplants are an effective treatment for many life-threatening diseases. Considerations for use include potential for cure, availability of a suitable donor, feasibility of using autologous stem cells, and risks of transplant-related mortality. Not addressed in this article, but also important, is consideration of the relative efficacy of conventional therapy in specific settings. The IBMTR and ABMTR offer a unique resource for examining the role of allogeneic and autologous transplants in cancer treatment.
骨髓移植是治疗许多危及生命疾病的有效方法。使用时需考虑的因素包括治愈的可能性、合适供体的可获得性、使用自体干细胞的可行性以及移植相关死亡率的风险。本文未涉及但同样重要的是,在特定情况下对传统疗法相对疗效的考量。国际骨髓移植登记处(IBMTR)和亚太骨髓移植登记处(ABMTR)为研究异基因和自体移植在癌症治疗中的作用提供了独特资源。