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Molecular cloning and sequencing of the gene encoding a sheep arginine vasopressin type 1a receptor.

作者信息

Hutchins A M, Phillips P A, Venter D J, Burrell L M, Johnston C I

机构信息

Department of Medicine, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia.

出版信息

Biochim Biophys Acta. 1995 Sep 19;1263(3):266-70. doi: 10.1016/0167-4781(95)00125-z.

DOI:10.1016/0167-4781(95)00125-z
PMID:7548217
Abstract

The gene for the sheep arginine vasopressin type 1a (V1a) receptor subtype was cloned from a genomic library. The deduced amino acid sequence shows characteristics of a G-protein coupled receptor and high sequence identity to human and rat V1a receptor sequences (81% and 73%, respectively). Reverse transcription-polymerase chain reaction (RT-PCR) analysis showed a tissue distribution consistent with a type V1a receptor. The genomic DNA (7.1 kb) contains a 1586 bp intron between the putative 6th and 7th transmembrane domains.

摘要

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