Peyrade F, Bondiau P Y, Lebrun C, Pivot X, de Jaureguibery J P, Thyss A
Service d'onco-hématologie, Centre Antoine-Laccassagne, Nice, France.
Bull Cancer. 1995 Jul;82(7):551-6.
Osteosarcoma of the vertebral column (OSV) is a rare tumor which represents 0.85% to 2% of all osteosarcomas. In 95% of the cases they manifest themselves through pains and 80% of other cases through neurological disorders. Usually located on lumbar vertebrae it can also be found on the rest of the vertebral column. Its radiologic aspect is one of lysis in 48% of cases but a condensation can also be met in 27% of cases. The differential diagnosis with an osteoblastoma is difficult and must be left in the hands of the pathologist who bases it on precise criteria (cellular pleomorphism, stroma, presence of giant cells...). The secondary osteosarcoma of the vertebral column represents 30% of all cases of OSV. The heterogeneity of the studies has made it difficult to quantify them. The prognosis of OSV is poor: survival average is of 15.3 months and relative risk of recurrence compared to a femoral lesion is of 3.9 months.
脊柱骨肉瘤（OSV）是一种罕见肿瘤，占所有骨肉瘤的0.85%至2%。95%的病例表现为疼痛，80%的其他病例表现为神经功能障碍。通常位于腰椎，也可在脊柱其他部位发现。其放射学表现为48%的病例呈溶骨性，但27%的病例也可出现骨质硬化。与骨母细胞瘤的鉴别诊断困难，必须由病理学家根据精确标准（细胞多形性、基质、巨细胞的存在等）来判断。脊柱继发性骨肉瘤占所有OSV病例的30%。研究的异质性使得难以对其进行量化。OSV的预后较差：平均生存期为15.3个月，与股骨病变相比，复发的相对风险为3.9个月。
