Matsubara S, Inoh M, Tarumi Y, Sato M, Takahara J
Minami Matsuyama Hospital.
Intern Med. 1995 Jun;34(6):514-9. doi: 10.2169/internalmedicine.34.514.
We report an outbreak of transient thyrotoxicosis that occurred between June and September 1993, in Matsuyama City, Ehime Prefecture. One hundred fifty-nine cases of thyrotoxicosis were identified, all in individuals without goiter. Thyroid autoantibodies were absent, and the serum thyroglobulin level was depressed. Ultrasonography of the thyroid disclosed no abnormal findings, while scintigraphy of the thyroid with 99mTc revealed poor uptake. About ten days after the onset, the serum thyroid hormone levels were normalized. No significant elevation of serum viral antibodies was found. These observations suggest that a thyrotoxicosis factitia may have been the cause of the present outbreak.
我们报告了1993年6月至9月期间在爱媛县松山市发生的一过性甲状腺毒症暴发。共确诊159例甲状腺毒症病例，所有患者均无甲状腺肿大。甲状腺自身抗体阴性，血清甲状腺球蛋白水平降低。甲状腺超声检查未发现异常，而99mTc甲状腺闪烁显像显示摄取不良。发病约10天后，血清甲状腺激素水平恢复正常。未发现血清病毒抗体显著升高。这些观察结果提示，人为甲状腺毒症可能是此次暴发的原因。
