Gorsky M, Dayan D
Section of Oral Pathology and Oral Medicine, Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Israel.
Eur J Cancer B Oral Oncol. 1995 May;31B(3):166-8. doi: 10.1016/0964-1955(95)00008-6.
The delay, stage at diagnosis and referral pattern of 543 oro/oropharyngeal cancer patients in Israel were investigated. About two-thirds of the malignancies were diagnosed at early stages. In more than two-thirds there was a delay of at least 2 months from the onset of signs and symptoms up to diagnosis, with a non-significant relationship between stage and delay. A significant correlation (P = 0.002) was found between delay and malignancy site. A delay of more than 4 months was observed in 71% of the patients with lip cancer. Cancers of the lip, palate and buccal mucosa were more frequently diagnosed at early stages. A significant correlation (P = 0.001) was found between stage at diagnosis and referral source. Although 86% of the cancers were diagnosed by physicians, nearly half were already at an advanced stage; when the cancers were diagnosed by dentists, 81% of the remainder were at early stages. No significant relationship was found between the referral medical profession and site of diagnosis. No nasopharyngeal, oropharyngeal or laryngeal cancers were diagnosed by dentists.
对以色列543例口腔/口咽癌患者的延迟情况、诊断分期及转诊模式进行了调查。约三分之二的恶性肿瘤在早期被诊断出来。超过三分之二的患者从出现症状到诊断至少延迟了2个月，分期与延迟之间无显著相关性。延迟与恶性肿瘤部位之间存在显著相关性（P = 0.002）。71%的唇癌患者观察到延迟超过4个月。唇癌、腭癌和颊黏膜癌更常于早期被诊断出来。诊断分期与转诊来源之间存在显著相关性（P = 0.001）。尽管86%的癌症由医生诊断，但近一半已处于晚期；当癌症由牙医诊断时，其余81%处于早期。转诊医学专业与诊断部位之间未发现显著关系。牙医未诊断出鼻咽癌、口咽癌或喉癌。
