Rusch V W
Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Lung Cancer. 1995 Jun;12 Suppl 2:S127-46. doi: 10.1016/s0169-5002(10)80011-x.
Malignant pleural mesothelioma is an uncommon cancer for which the major risk factor is prior asbestos exposure. During the past decade, there has been progress in the diagnosis, staging and biology of mesothelioma. Treatment remains controversial and ranges from supportive care alone to aggressive multimodality therapy. Prospective clinical trials in carefully staged patients are needed to determine what approaches to treatment may confer a survival benefit.
恶性胸膜间皮瘤是一种罕见的癌症,其主要危险因素是既往接触石棉。在过去十年中,间皮瘤的诊断、分期和生物学方面取得了进展。治疗仍然存在争议,范围从单纯的支持性治疗到积极的多模式治疗。需要对分期明确的患者进行前瞻性临床试验,以确定哪些治疗方法可能带来生存获益。