Gee A S, Durdey P
University Department of Surgery, Bristol Royal Infirmary, UK.
Br J Surg. 1995 Sep;82(9):1179-82. doi: 10.1002/bjs.1800820910.
A proportion of patients with faecal incontinence experience debilitating urgency of defaecation and urge incontinence. This study prospectively assessed 56 faecally incontinent patients by means of standard interview, physical examination and anorectal physiology. Patients with urge incontinence, when compared with those without urge incontinence, were symptomatically worse, had had more vaginal deliveries and had more bowel actions each day. Physiological tests included anal manometry, anal electrosensitivity, pudendal nerve terminal motor latency and a standard proctometrogram. The only physiological differences between the groups were a reduction in voluntary squeeze pressure (median (interquartile range (i.q.r.)) 43 (26-67) versus 67 (45-122) mmHg, P = 0.01) and a smaller percentage change in pressure-volume, an integral of sphincter length and squeeze (median (i.q.r.) 43.5 (0-289) versus 247 (71-455), P = 0.02), in those with urgency. The authors conclude that urge incontinence is associated with impairment of the striated musculature of the anal sphincter complex.
一部分大便失禁患者会经历令人虚弱的排便紧迫感和急迫性尿失禁。本研究通过标准访谈、体格检查和肛肠生理学方法对56例大便失禁患者进行了前瞻性评估。与无急迫性尿失禁的患者相比,急迫性尿失禁患者症状更严重,阴道分娩次数更多,且每天排便次数更多。生理测试包括肛门测压、肛门电敏感性、阴部神经终末运动潜伏期和标准直肠测压图。两组之间唯一的生理差异在于,有急迫感的患者其自主收缩压降低(中位数(四分位间距(i.q.r.))为43(26 - 67)mmHg,而无急迫感患者为67(45 - 122)mmHg,P = 0.01),以及压力 - 容积变化百分比更小(压力 - 容积是括约肌长度和收缩的积分,中位数(i.q.r.)为43.5(0 - 289),而无急迫感患者为247(71 - 455),P = 0.02)。作者得出结论,急迫性尿失禁与肛门括约肌复合体的横纹肌组织受损有关。