淋巴细胞生成。控制B细胞发育的转录因子。
Lymphopoiesis. Transcription factors controlling B-cell development.
作者信息
Desiderio S
机构信息
Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
出版信息
Curr Biol. 1995 Jun 1;5(6):605-8. doi: 10.1016/s0960-9822(95)00121-7.
PMID:7552167
Abstract
Two structurally dissimilar transcriptional regulators, E2A and Pax-5, have been shown to play essential roles in B-cell development; the p50 subunit of NF kappa B, by contrast, is required for normal immune responses.
摘要
两种结构不同的转录调节因子E2A和Pax - 5已被证明在B细胞发育中起关键作用；相比之下，NF-κB的p50亚基是正常免疫反应所必需的。
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