[预防离子型碘化造影剂不良反应的预处理。对比研究]

[Premedication for the prevention of adverse reactions to ionic iodized contrast media. Comparative study].

作者信息

White Mediaceja V L, Alfonso Fernández L A, Ginard Cabañas A, Gómez Echevarría A H

机构信息

Servicio de alergología Hospital CQ Hermanos Ameijeiras, Centro Habana, Cuba.

出版信息

Rev Alerg Mex. 1995 May-Jun;42(3):45-8.

PMID:7552182

Abstract

A study comparing two pretreatment protocols to prevent adverse reactions to iodinated radiocontrast media (IRCM) was performed in 45 adults patients. They followed inclusion and exclusion criteria. Pretreatment protocol A was within 12 hours before using the IRCM and pretreatment protocol B was for 72 hours before. A corticosteroid and two H2 receptor antagonists were given on both protocols. We managed these protocols by an aleatory way, so 22 patients received protocol A and 23 patients received protocol B. Excellent results were found in 63.6% and good results were found in 36.4% for protocol A. Excellent results were found in 78.2% and good results were found in 21.8% for protocol B. However, no statistically differences were detected for both protocols (p = 0.451).

摘要

对45例成年患者进行了一项比较两种预处理方案以预防碘造影剂（IRCM）不良反应的研究。他们遵循纳入和排除标准。预处理方案A在使用IRCM前12小时内进行，预处理方案B在使用前72小时进行。两种方案均给予一种皮质类固醇和两种H2受体拮抗剂。我们以随机方式实施这些方案，因此22例患者接受方案A，23例患者接受方案B。方案A的优良率分别为63.6%和36.4%。方案B的优良率分别为78.2%和21.8%。然而，两种方案之间未检测到统计学差异（p = 0.451）。