Bruce L L, Neary T J
Department of Biomedical Sciences, Creighton University, Omaha, NE 68178, USA.
Brain Behav Evol. 1995;46(1):14-29. doi: 10.1159/000113255.
Afferent projections to the ventromedial hypothalamic nucleus (VMH) of a lizard, Gekko gecko, were studied with wheat germ agglutinin conjugated to horseradish peroxidase. Results indicated that the shell and core areas of the VMH are largely innervated by different telencephalic nuclei but similar brain-stem nuclei. The common brainstem projections include the superior raphe, two isthmal populations (the ventral isthmal nucleus and parvocellular isthmal nucleus), and a dorsal thalamic projection from the posteroventral nucleus. Brainstem projections to the shell but not to the core of the VMH arise from the laterodorsal tegmental nucleus. Telencephalic projections to the VMH core originate from the ventrolateral septum, centromedial DVR, lateral amygdala, medial amygdala, interstitial amygdala, and ventral anterior amygdala. Telencephalic projections to the VMH shell come from the ventral pallidum, the anterior septal nucleus, the dorsal septal nucleus, the striatoamygdalar area, and the ventral posterior amygdala. These results, combined with connectional and topological information from other studies in amphibians, reptiles, and mammals, will be used to suggest homologies between a number of limbic areas, including several amygdalar nuclei.
利用与辣根过氧化物酶结合的小麦胚芽凝集素，对一种蜥蜴——蛤蚧的下丘脑腹内侧核（VMH）的传入投射进行了研究。结果表明，VMH的壳区和核心区在很大程度上由不同的端脑核支配，但由相似的脑干核支配。常见的脑干投射包括上缝核、两个峡部核群（腹侧峡部核和小细胞峡部核）以及来自后腹侧核的背侧丘脑投射。投射到VMH壳区而非核心区的脑干投射起源于外侧背侧被盖核。投射到VMH核心区的端脑投射起源于腹外侧隔、中央内侧DVR、外侧杏仁核、内侧杏仁核、间质杏仁核和腹侧前杏仁核。投射到VMH壳区的端脑投射来自腹侧苍白球、前隔核、背侧隔核、纹状体杏仁核区和腹侧后杏仁核。这些结果，结合来自两栖动物、爬行动物和哺乳动物其他研究的连接和拓扑信息，将用于表明包括几个杏仁核在内的一些边缘区域之间的同源性。
