Lucas R L, Salm A K
Department of Biology, West Virginia University, Morgantown 26506-6057, USA.
Brain Res. 1995 May 29;681(1-2):218-22. doi: 10.1016/0006-8993(95)00296-3.
The effects of the peptides oxytocin and vasopressin on the proliferation of cultured cortical and hypothalamic astroglia were assessed by two corroborative methods. Both hemocytometer cell counts, and immunocytochemistry for bromodeoxyuridine (BrdU) incorporation and glial fibrillary acidic protein (GFAP) expression indicate that oxytocin increases the rate of proliferation of both cortical and hypothalamic astroglia. While vasopressin also had an effect on cortical cells, no conclusive evidence for vasopressin affecting proliferation of hypothalamic astroglia was found.
采用两种相互印证的方法评估了肽类物质催产素和加压素对培养的皮质和下丘脑星形胶质细胞增殖的影响。血细胞计数器细胞计数以及针对溴脱氧尿苷（BrdU）掺入和胶质纤维酸性蛋白（GFAP）表达的免疫细胞化学分析均表明，催产素可提高皮质和下丘脑星形胶质细胞的增殖速率。虽然加压素对皮质细胞也有影响，但未发现加压素影响下丘脑星形胶质细胞增殖的确凿证据。
