Brehm D M, Vite C H, Steinberg H S, Haviland J, van Winkle T
Department of Small Animal Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010, USA.
J Am Anim Hosp Assoc. 1995 Jul-Aug;31(4):349-59. doi: 10.5326/15473317-31-4-349.
Fifty-one cases of canine peripheral nerve sheath tumors were reviewed. Signalment, presenting clinical signs, duration of clinical signs, physical and neurological examination findings, results of diagnostic procedures, type of surgery performed, tumor location, relapse-free intervals and survival times, and causes of death were evaluated. Tumors were divided into three anatomical groups: tumors involving nerves distal to the brachial or lumbosacral plexus (Peripheral Group), tumors involving nerves of the brachial or lumbosacral plexus (Plexus Group), and tumors involving the vertebral canal (Root Group). The most common clinical findings were unilateral forelimb lameness and muscle atrophy. The most useful diagnostic tests were myelography and electromyography. Although there was no significant difference, dogs in the Root Group tended to have shorter relapse-free intervals and survival times than dogs in the Plexus Group. The overall prognosis for surgical management of peripheral nerve sheath tumors is guarded to poor.
回顾了51例犬外周神经鞘瘤病例。对信号、出现的临床症状、临床症状持续时间、体格和神经学检查结果、诊断程序结果、所进行的手术类型、肿瘤位置、无复发间隔和生存时间以及死亡原因进行了评估。肿瘤分为三个解剖学组:累及臂丛或腰骶丛远端神经的肿瘤(外周组)、累及臂丛或腰骶丛神经的肿瘤(丛组)以及累及椎管的肿瘤(根部组)。最常见的临床症状是单侧前肢跛行和肌肉萎缩。最有用的诊断测试是脊髓造影和肌电图。虽然没有显著差异,但根部组的犬无复发间隔和生存时间往往比丛组的犬短。外周神经鞘瘤手术治疗的总体预后为谨慎至不良。