Stave R, Myren J, Brandtzaeg P, Gjone E
Scand J Gastroenterol. 1978;13(3):293-8. doi: 10.3109/00365527809179823.
The distribution of parietal cells in the body mucosa, and of G cells in the antral mucosa, was quantitatively mapped in resected stomachs from 42 patients (12 with gastric ulcer, 11 with duodenal ucler, 14 with duodenal ulcer and uremia, and 5 with gastric cancer) who preoperatively had had their gastric acid secretion measured. In the material as a whole there was a significant positive correlation between the parietal-cell density and maximal acid output (MAO), and a significant negative correlation between the parietal-cell density and patient age. A significant positive correlation was found between the antral G-cell mass and basal acid output (BAO). When the individual patient categories were analyzed, the correlation between parietal-cell density and MAO were significant in the group with duodenal ulcer and uremia, and in the group with gastric cancer. Correlation between parietal-cell density and age was found only in the group with duodenal ulcer and uremia. There was no correlation between the parietal-cell density and various parameters of the antral G-cell population in the material as a whole or in any of the individual groups.
对42例患者（12例胃溃疡、11例十二指肠溃疡、14例十二指肠溃疡合并尿毒症、5例胃癌）切除的胃进行定量测绘，这些患者术前均已测定胃酸分泌情况，以了解胃体黏膜壁细胞及胃窦黏膜G细胞的分布。在整个样本中，壁细胞密度与最大酸排量（MAO）之间存在显著正相关，壁细胞密度与患者年龄之间存在显著负相关。胃窦G细胞量与基础酸排量（BAO）之间存在显著正相关。对各患者类别进行分析时，十二指肠溃疡合并尿毒症组和胃癌组中壁细胞密度与MAO之间的相关性显著。仅在十二指肠溃疡合并尿毒症组中发现壁细胞密度与年龄之间存在相关性。在整个样本或任何单个组中，壁细胞密度与胃窦G细胞群体的各种参数之间均无相关性。
