Patterson S M, Matthews K A, Allen M T, Owens J F
Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA.
Health Psychol. 1995 Jul;14(4):319-24. doi: 10.1037//0278-6133.14.4.319.
This study examined the effects of psychological stress on hemoconcentration in women. Hematologic and hemodynamic variables were assessed in 17 women before and after a 3-min speech task. Significant changes in hematocrit, hemoglobin levels, red and white blood cell (WBC) count, and calculated plasma volume occurred during psychological stress (all ps < .05). Significant increases were also observed for total cholesterol, triglycerides, high density lipoprotein cholesterol, low density lipoprotein cholesterol, and free fatty acid (FFA; all ps < .05) during stress. After statistically correcting for the hemoconcentration effects of decreased plasma volume during stress, only WBC count and FFA concentration remained significantly elevated during the stress task (p < .006 and p < .05, respectively). In sum, acute stress alters hemoconcentration in women, which in turn can account for most stress-induced changes in lipids.
本研究考察了心理压力对女性血液浓缩的影响。在17名女性完成3分钟演讲任务前后，对其血液学和血液动力学变量进行了评估。心理压力期间，血细胞比容、血红蛋白水平、红细胞和白细胞（WBC）计数以及计算得出的血浆容量均发生了显著变化（所有p值均<0.05）。压力期间，总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和游离脂肪酸（FFA）也均显著升高（所有p值均<0.05）。在对压力期间血浆容量减少导致的血液浓缩效应进行统计学校正后，压力任务期间只有白细胞计数和FFA浓度仍显著升高（分别为p<0.006和p<0.05）。总之，急性压力会改变女性的血液浓缩，这反过来又可以解释大多数压力诱导的血脂变化。
