Stentella P, Pace S, Villani C, Palazzetti P L, Di Renzi F, Stolfi G, Frega A
2nd Department of Obstetrics and Gynecology, University of Rome La Sapienza, Italy.
Eur J Gynaecol Oncol. 1995;16(4):282-9.
Between 1984 and 1992, the CO2 laser was used to treat 341 patients affected by CIN of various degrees. On the basis of specific indications these patients underwent vaporization or conization. Two hundred and twenty eight patients underwent vaporization of intraepithelial lesions, 221 (96.92%) of whom were free of disease after one laser treatment, as observed during the subsequent years of follow-up. In 105 out of the 113 patients treated with conization the cone margin was free of disease. One hundred and one (96.19%) of the these 105 patients had no evidence of disease after one year of follow-up. In the remaining 8 (7.07%) cases examination of the cone revealed the presence of invasive carcinoma. The major complication was vaginal discharge observed in 115 (33.72%) patients. The CO2 laser is a very effective therapeutic procedure for the treatment of intraepithelial lesions of the cervix and permits to preserve reproductive function and anatomic integrity.
1984年至1992年间，二氧化碳激光用于治疗341例不同程度宫颈上皮内瘤变（CIN）患者。根据具体指征，这些患者接受了汽化或锥形切除术。228例患者接受了上皮内病变汽化术，在随后的随访年份中观察到，其中221例（96.92%）经一次激光治疗后无疾病。在113例行锥形切除术的患者中，105例切缘无疾病。这105例患者中有101例（96.19%）在随访一年后无疾病证据。其余8例（7.07%）锥形切除检查发现存在浸润癌。主要并发症为115例（33.72%）患者出现阴道分泌物。二氧化碳激光是治疗宫颈上皮内病变的一种非常有效的治疗方法，并且能够保留生殖功能和解剖完整性。
