Simpson J M, Patel J S, Ispahani P
Nottingham Neonatal Service, Queen's Medical Centre and City Hospital, United Kingdom.
Eur J Pediatr. 1995 Jul;154(7):563-6. doi: 10.1007/BF02074835.
A series of 11 cases of invasive infection with Streptococcus pneumoniae, occurring over an 11-year period, is reported. Eight of the 11 cases occurred during the final 2 years of the study suggesting that the incidence of infection may be increasing. Infection carries a high mortality (3/11). Morbidity includes meningitis, convulsions and respiratory failure. In one case S. pneumoniae meningitis occurred in both mother and newborn. Most mothers who carried the organism were asymptomatic at the time of delivery.
S. pneumoniae should be specifically sought in swabs taken from the pregnant mother and newborn and if isolated, even in the absence of symptoms, antibiotic therapy against the organism should be strongly considered.
报告了一系列11例肺炎链球菌侵袭性感染病例,这些病例发生在11年期间。11例中的8例发生在研究的最后2年,提示感染发病率可能在上升。感染死亡率很高(11例中有3例)。发病情况包括脑膜炎、惊厥和呼吸衰竭。有1例母亲和新生儿均发生了肺炎链球菌脑膜炎。大多数携带该病菌的母亲在分娩时无症状。
应特别在取自孕妇和新生儿的拭子中查找肺炎链球菌,若分离出该病菌,即使无症状,也应强烈考虑针对该病菌进行抗生素治疗。