Bouget F Y, Gerttula S, Quatrano R S
Department of Biology, University of North Carolina, Chapel Hill 27599-3280, USA.
Dev Biol. 1995 Sep;171(1):258-61. doi: 10.1006/dbio.1995.1277.
Asymmetrical distribution of mRNA has been associated with polarization and cell fate determination during early development of animal embryos. In this report we determine the distribution pattern of poly(A)+ RNA during early embryogenesis of the brown alga Fucus. Poly(A)+ RNA is symmetrically distributed in the egg and early zygote. Shortly after the polar axis is established, poly(A)+ RNA becomes segregated to the thallus pole of the zygote. Following cytokinesis, most of poly(A)+ RNA is partitioned into the thallus cell. We show that the spatial redistribution of poly(A)+ RNA requires intact microfilaments and the fixation of the polar axis, but is not dependent upon polarized growth of the rhizoid, intact microtubules, or orientation of the division plane.
mRNA的不对称分布与动物胚胎早期发育过程中的细胞极化和细胞命运决定有关。在本报告中，我们确定了褐藻墨角藻早期胚胎发生过程中聚腺苷酸（poly(A)）+ RNA的分布模式。聚腺苷酸（poly(A)）+ RNA在卵细胞和早期合子中呈对称分布。在极轴建立后不久，聚腺苷酸（poly(A)）+ RNA开始分离到合子的叶状体极。胞质分裂后，大部分聚腺苷酸（poly(A)）+ RNA被分配到叶状体细胞中。我们发现，聚腺苷酸（poly(A)）+ RNA的空间重新分布需要完整的微丝和极轴的固定，但不依赖于假根的极化生长、完整的微管或分裂平面的方向。
