Toledo-Pereyra L H, Rodríguez F J
Departamento de Investigación Quirúrgica y Transplantes, Borgess Medical Center, Kalamazoo, MI, 49001, USA.
Gac Med Mex. 1994 Nov-Dec;130(6):487-94.
Since the original description of the pancreas transplant technique in animals, initially as a pedicle transplant in 1892, free graft in 1913, and then as a vascularized organ in 1927, there have been several changes in the handling of the exocrine secretions, as well as the vascular anastomoses, and the posttransplant function in relation to the immunosuppressive therapy. The surgical technical changes have included the ligature of the duct, the free drainage to the abdominal cavity, the pancreas transplant with a duodenal segment, the chemical occlusion of the duct, and its drainage to the intestine or to the bladder with a duodenal segment. This last technique remains as the standard technique currently used for pancreas transplantation, along with the combined transplant of the kidney. This work reviews the historical aspects, the evolution of the experimental and clinical surgical techniques, and the current results associated with the surgical management of pancreas transplantation.
自1892年首次在动物身上描述胰腺移植技术以来，最初是带蒂移植，1913年是游离移植，然后在1927年作为血管化器官移植，在处理外分泌、血管吻合以及与免疫抑制治疗相关的移植后功能方面发生了一些变化。手术技术的改变包括结扎胰管、向腹腔自由引流、带十二指肠段的胰腺移植、胰管的化学闭塞以及通过十二指肠段将其引流至肠道或膀胱。最后这项技术与肾联合移植一起，仍然是目前胰腺移植所采用的标准技术。本文回顾了胰腺移植的历史背景、实验和临床手术技术的演变以及与胰腺移植手术管理相关的当前结果。
