Lewis M P, Khoo D E, Spencer J
Department of Surgery, Royal Postgraduate Medical School, Hammersmith Hospital, London.
Gut. 1995 Aug;37(2):187-90. doi: 10.1136/gut.37.2.187.
Over a nine year period a total of 137 patients were investigated for obscure gastrointestinal bleeding on one surgical unit. In 20 patients visceral angiography strongly suggested the presence of caecal or right colonic angiodysplasia. These patients were treated by an appropriate colectomy and they are not considered further in this study. Similarly lesions of the small bowel detected by preoperative investigations are not considered here. Fifty five patients were offered diagnostic laparotomy after the failure of other investigations to establish a diagnosis. Two patients refused. A diagnostic laparotomy was performed in the remaining 53. At operation if no visible lesion was seen an on table enteroscopy was performed using a colonoscope passed per oram and, if necessary, per anum. In nine (17%) patients no cause for bleeding was found. In 18 (34%) patients there was a small bowel vascular anomaly, in 14 (26%) a small bowel tumour, in four (7.5%) a bleeding Meckel's diverticulum, and in eight (15%) other miscellaneous lesions. Laparotomy, with on table enteroscopy where indicated, elucidated the cause of bleeding in 44 patients (83%). It was associated, however, with a postoperative death rate of 7.5% (four patients). After seemingly appropriate surgery, rebleeding occurred in 14 patients (26%). Of 18 patients with small bowel vascular anomalies seven rebled (39%), at an average follow up interval of 32 months.
在九年的时间里,一个外科科室共对137例不明原因的胃肠道出血患者进行了调查。20例患者的内脏血管造影强烈提示存在盲肠或右半结肠血管发育异常。这些患者接受了适当的结肠切除术治疗,本研究不再对他们作进一步考虑。同样,术前检查发现的小肠病变也不在此研究范围内。在其他检查未能确诊后,55例患者接受了诊断性剖腹探查术。2例患者拒绝。其余53例患者进行了诊断性剖腹探查术。手术中若未发现可见病变,则经口(必要时经肛门)插入结肠镜进行术中肠镜检查。9例(17%)患者未发现出血原因。18例(34%)患者存在小肠血管异常,14例(26%)存在小肠肿瘤,4例(7.5%)存在出血性梅克尔憩室,8例(15%)存在其他杂类病变。剖腹探查术(必要时进行术中肠镜检查)明确了44例患者(83%)的出血原因。然而,其术后死亡率为7.5%(4例患者)。在看似适当的手术后,14例患者(26%)再次出血。18例小肠血管异常患者中有7例再次出血(39%),平均随访间隔为32个月。