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A new family of retroviral long terminal repeat elements in the human genome identified by their homologies to an element 5' to the spider monkey haptoglobin gene.

作者信息

Erickson L M, Maeda N

机构信息

Curriculum of Genetics, University of North Carolina, Chapel Hill, USA.

出版信息

Genomics. 1995 Jun 10;27(3):531-4. doi: 10.1006/geno.1995.1087.

DOI:10.1006/geno.1995.1087
PMID:7558037
Abstract

A new family of retroviral long terminal repeats that we name Spm-LTR has been identified as a result of DNA sequence comparisons between the entire GenBank databank and an element, SPHP, located 5' to the haptoglobin gene of spider monkeys. The 18 human Spm-LTR sequences so identified fall into three subtypes. There is no sequence similarity between Spm-LTR elements and any endogenous retroviral LTR sequences previously reported except for general features that define LTRs. However, a previously described repeated sequence (MER-4) forms a portion of the Spm-LTR sequence.

摘要

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