Ice R D
Neely Nuclear Research Center, Georgia Institute of Technology, Atlanta 30332-042, USA.
Health Phys. 1995 Nov;69(5):721-7. doi: 10.1097/00004032-199511000-00007.
Radionuclide production for medical use originally was incidental to isotope discoveries by physicists and chemists. Once the available radionuclides were identified they were evaluated for potential medical use. Hevesy first used 32P in 1935 to study phosphorous metabolism in rats. Since that time, the development of cyclotrons, linear accelerators, and nuclear reactors have produced hundreds of radionuclides for potential medical use. The history of medical radionuclide production represents an evolutionary, interdisciplinary development of applied nuclear technology. Today the technology is represented by a mature industry and provides medical benefits to millions of patients annually.
医用放射性核素的生产最初是物理学家和化学家发现同位素时的附带成果。一旦确定了可用的放射性核素，便会对其潜在的医学用途进行评估。1935年，赫维西首次使用32P来研究大鼠的磷代谢。从那时起，回旋加速器、直线加速器和核反应堆的发展已产生了数百种有潜在医学用途的放射性核素。医用放射性核素生产的历史代表了应用核技术的一个渐进的、跨学科的发展过程。如今，这项技术已发展成为一个成熟的产业，每年为数百万患者带来医疗益处。
