LeSon S, Gershwin M E
Division of Rheumatology, Allergy, and Clinical Immunology, University of California Davis, School of Medicine 95616, USA.
J Asthma. 1995;32(2):97-104. doi: 10.3109/02770909509083230.
Our object was to describe demographic data from a population of adult asthmatics admitted to a regional tertiary medical center to identify risk factors for intubation. We performed a retrospective cohort study of all asthma admissions (International Classification of Diseases, Ninth Revision, Code 493.9) excluding cases with chronic obstructive pulmonary disease. This included all patients with asthma 20 years and above admitted to the University of California Davis Medical Center, Sacramento, from January 1, 1990 to June 30, 1993. A total of 375 asthma admissions were reviewed. There were 244 women (29 intubated) and 131 men (13 intubated) with a mean age of 40.7 (range 20-72) years. Of this group, 131 people were white, 140 black, 56 Hispanic, 42 Asian, and 6 American Indian. By National Heart, Lung, and Blood Institute Guidelines, there were 101 mild, 181 moderate, and 93 severe cases. Significant risk parameters identified for intubation were psychosocial problems [odds ratio (O.R.) 9.3; 95% confidence interval (C.I.) 6.8, 12.7], low socioeconomic group (O.R. 2.9; 95% C.I. 1.5, 5.8), little formal education (O.R. 5.4; 95% C.I. 2.8, 10.2), atopic allergy (O.R. 11.7; 95% C.I. 5.7, 23.7), duration of asthma > or = 15 years (O.R. 2.6; 95% C.I. 1.3, 5.3), previous intubation (O.R. 14.0; 95% C.I. 7.6, 25.6), upper respiratory infection (O.R. 4.0; 95% C.I. 2.2, 7.5), hospital admission for asthma within the last year (O.R. 5.3; 95% C.I. 2.7, 10.4), emergency room visit within the last year (O.R. 8.8; 95% C.I. 3.9, 20.1), and steroid dependency (O.R. 5.5; 95% C.I. 3.0, 10.2).(ABSTRACT TRUNCATED AT 250 WORDS)
我们的目的是描述入住某地区三级医疗中心的成年哮喘患者的人口统计学数据，以确定插管的风险因素。我们对所有哮喘住院病例（国际疾病分类第九版，编码493.9）进行了一项回顾性队列研究，排除了慢性阻塞性肺疾病病例。这包括1990年1月1日至1993年6月30日期间入住加利福尼亚大学戴维斯分校萨克拉门托医疗中心的所有20岁及以上的哮喘患者。共审查了375例哮喘住院病例。其中有244名女性（29例插管）和131名男性（13例插管），平均年龄为40.7岁（范围20 - 72岁）。在这组患者中，131人为白人，140人为黑人，56人为西班牙裔，42人为亚洲人，6人为美洲印第安人。根据美国国立心肺血液研究所的指南，有101例轻度、181例中度和93例重度病例。确定的插管显著风险参数包括社会心理问题[比值比（O.R.）9.3；95%置信区间（C.I.）6.8, 12.7]、低社会经济群体（O.R. 2.9；95% C.I. 1.5, 5.8）、正规教育程度低（O.R. 5.4；95% C.I. 2.8, 10.2）、特应性过敏（O.R. 11.7；95% C.I. 5.7, 23.7）、哮喘病程≥15年（O.R. 2.6；95% C.I. 1.3, 5.3）、既往插管史（O.R. 14.0；95% C.I. 7.6, 25.6）、上呼吸道感染（O.R. 4.0；95% C.I. 2.2, 7.5）、过去一年内因哮喘住院（O.R. 5.3；95% C.I. 2.7, 10.4）、过去一年内急诊就诊（O.R. 8.8；95% C.I. 3.9, 20.1）以及类固醇依赖（O.R. 5.5；95% C.I. 3.0, 10.2）。（摘要截断于250字）
