Sun M, Shioya T, Wang R J, Ishiwata T, Naito Z, Qiao Y, Asano G, Ohaki Y, Kunimi T, Takeuchi T
Department of Pathology, Nippon Medical School.
Nihon Ika Daigaku Zasshi. 1995 Aug;62(4):391-5. doi: 10.1272/jnms1923.62.391.
Two autopsy cases (69 and 87-year-old women) of malignant mixed müllerian tumor (MMMT) following radiation therapy for uterine cervical cancer sixteen and twenty years ago respectively were reported. They were admitted due to abdominal pain and diagnosed as ileus. In the first case, CT examination revealed a tumor measuring about 8 x 10 cm in size in the uterine posterior wall. Recurrence of the uterine cancer was suspected and hysterooophorectomy combined with sigmoidectomy was performed. In the second case, artificial anus formation was performed because of sigmoid stricture by the invasion of the tumor. Histologically, tumors in both cases were composed of carcinomatous and sarcomatous components including heterologous elements such as cartilage. The patients died of extensive spreads and metastasis in the liver and alimentary tract.
