Agha A, Hashimoto K
Department of Dermatology & Syphilology, Wayne State University School of Medicine, Detroit, MI 48201, USA.
J Dermatol. 1995 Jul;22(7):520-3. doi: 10.1111/j.1346-8138.1995.tb03437.x.
This is a case report of multiple lentigines (Leopard Syndrome) with Chiari malformation, i.e. a herniation of the cerebellum into the foramen magnum. This male patient had generalized multiple lentigines since birth, and the lesions spread steadily, involving the scalp but sparing all mucous membranes. Organ system involvements included heart murmur, ocular hypertelorism, and retardation of growth.
这是一篇关于多发性雀斑样痣（豹皮综合征）合并Chiari畸形（即小脑疝入枕骨大孔）的病例报告。该男性患者自出生起即患有全身性多发性雀斑样痣，皮损持续扩散，累及头皮但不累及所有黏膜。器官系统受累包括心脏杂音、眼距增宽和生长发育迟缓。
