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[原代单层培养成年大鼠肝细胞的亚表面池(作者译)]

[Subsurface cisterns of adult rat hepatocytes in primary monolayer cultures (author's transl)].

作者信息

Pellin A

出版信息

Arch Anat Microsc Morphol Exp. 1978;67(4):213-23.

PMID:756219
Abstract

Primary cultures of adult rat hepatocytes are a good model for the study of SSC, because they appear in a great number of cells when these form trabecular structures in the culture. The SSC seem to be multifunctional features. They have not only one and the same function in the variety of cells in which they exist. Their localization in the hepatocytes point to an implication in cell adhesion mechanisms. The images also suggest a possible participation in cell membrane repair phenomena. The SSC are a differentiate portion of endoplasmic reticulum for the repairment of cell membrane portions damaged in the isolation of hepatocytes.

摘要

成年大鼠肝细胞的原代培养是研究胆小管(SSC)的良好模型,因为当这些细胞在培养物中形成小梁结构时,它们会大量出现。胆小管似乎具有多种功能特性。它们在其存在的各种细胞中不仅具有相同的功能。它们在肝细胞中的定位表明其参与细胞粘附机制。这些图像还表明可能参与细胞膜修复现象。胆小管是内质网的一个分化部分,用于修复肝细胞分离过程中受损的细胞膜部分。

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