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[A群脑膜炎奈瑟菌糖蛋白的抗原特性及多种生物学特性]

[Antigenic characteristics and various biological properties of glycoprotein from Neisseria meningitidis of serological group A].

作者信息

Ezepchuk Iu V, Kostiukova N N, Beĭlbaeva M L, Polianin V A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1978 Jan(1):79-84.

PMID:75626
Abstract

It was shown that the antigen determining the group specificity of meningococcus belonging to serological group A was of mixed polysaccharide-protein nature. Carbohydrate component is responsible for the interaction with the group-specific antibodies in this antigen. Glycoprotein can be isolated both from the cells and from the culture fluid where it passes during the N. meningitidis cultivation in fluid nutrient medium. The described antigen possesses no properties of endotoxin.

摘要

结果表明,决定属于血清群A的脑膜炎球菌群特异性的抗原具有多糖 - 蛋白质混合性质。碳水化合物成分负责该抗原与群特异性抗体的相互作用。糖蛋白既可以从细胞中分离出来,也可以从脑膜炎奈瑟菌在液体营养培养基中培养时其经过的培养液中分离出来。所述抗原不具有内毒素的特性。

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