How does the MRP/GS-X pump export doxorubicin?

Suppr

超能文献

作者信息

Ishikawa T, Akimaru K, Kuo M T, Priebe W, Suzuki M

出版信息

J Natl Cancer Inst. 1995 Nov 1;87(21):1639-40. doi: 10.1093/jnci/87.21.1639.

DOI:10.1093/jnci/87.21.1639

PMID:7563208

Abstract

摘要

相似文献

How does the MRP/GS-X pump export doxorubicin?

J Natl Cancer Inst. 1995 Nov 1;87(21):1639-40. doi: 10.1093/jnci/87.21.1639.

MRP is frequently expressed in human lung-cancer cell lines, in non-small-cell lung cancer and in normal lungs.多药耐药相关蛋白（MRP）在人肺癌细胞系、非小细胞肺癌及正常肺组织中均有频繁表达。

Int J Cancer. 1996 Jun 11;66(6):760-7. doi: 10.1002/(SICI)1097-0215(19960611)66:6<760::AID-IJC9>3.0.CO;2-Y.

Direct interaction between a quinoline derivative, MS-209, and multidrug resistance protein (MRP) in human gastric cancer cells.喹啉衍生物MS-209与人胃癌细胞中多药耐药蛋白（MRP）之间的直接相互作用。

Biochem Biophys Res Commun. 1999 Feb 24;255(3):618-24. doi: 10.1006/bbrc.1999.0245.

Re: How does the MRP/GS-X pump export doxorubicin?

J Natl Cancer Inst. 1996 Apr 3;88(7):466-8. doi: 10.1093/jnci/88.7.466.

[Drug distribution, resistance to cytostatics and disease pathogenesis: many roles of ABC proteins].[药物分布、对细胞抑制剂的耐药性与疾病发病机制：ABC蛋白的多种作用]

Lakartidningen. 2004 Jan 22;101(4):282-7.

The 4'-O-benzylated doxorubicin analog WP744 overcomes resistance mediated by P-glycoprotein, multidrug resistance protein and breast cancer resistance protein in cell lines and acute myeloid leukemia cells.4'-O-苄基化阿霉素类似物WP744克服了细胞系和急性髓系白血病细胞中由P-糖蛋白、多药耐药蛋白和乳腺癌耐药蛋白介导的耐药性。

Invest New Drugs. 2007 Apr;25(2):115-22. doi: 10.1007/s10637-006-9018-3. Epub 2006 Oct 28.

Doxorubicin- and daunorubicin-glutathione conjugates, but not unconjugated drugs, competitively inhibit leukotriene C4 transport mediated by MRP/GS-X pump.阿霉素和柔红霉素与谷胱甘肽的结合物，而非未结合的药物，能竞争性抑制由多药耐药相关蛋白/谷胱甘肽-S-转移酶-X泵介导的白三烯C4转运。

Biochem Biophys Res Commun. 1998 Jun 29;247(3):859-63. doi: 10.1006/bbrc.1998.8887.

The anthracycline resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell line.蒽环类抗生素耐药相关（ara）基因，一种与人类白血病细胞系多药耐药相关的新基因。

Br J Cancer. 1996 Nov;74(9):1331-5. doi: 10.1038/bjc.1996.545.

Modulation of multidrug resistance in a cancer cell line by anti-multidrug resistance-associated protein (MRP) ribozyme.抗多药耐药相关蛋白（MRP）核酶对癌细胞系多药耐药性的调控

Anticancer Res. 2001 Mar-Apr;21(2A):879-85.

Multidrug resistance-associated protein (MRP) in haematological malignancies.血液系统恶性肿瘤中的多药耐药相关蛋白（MRP）

Leuk Lymphoma. 1996 Feb;20(5-6):381-7. doi: 10.3109/10428199609052419.

引用本文的文献

Drug resistance features and S-phase fraction as possible determinants for drug response in a panel of human ovarian cancer xenografts.一组人卵巢癌异种移植模型中耐药特征和S期分数作为药物反应可能决定因素的研究

Br J Cancer. 2000 Oct;83(7):921-7. doi: 10.1054/bjoc.2000.1373.

ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1.多药耐药蛋白MRP1介导的化疗药物的ATP和谷胱甘肽依赖性转运

Br J Pharmacol. 1999 Feb;126(3):681-8. doi: 10.1038/sj.bjp.0702360.

Comparative evaluation by semiquantitative reverse transcriptase polymerase chain reaction of MDR1, MRP and GSTp gene expression in breast carcinomas.通过半定量逆转录聚合酶链反应对乳腺癌中MDR1、MRP和GSTp基因表达进行比较评估。

Br J Cancer. 1998 Mar;77(5):694-702. doi: 10.1038/bjc.1998.115.

Induction of MRP/GS-X pump and cellular resistance to anticancer prostaglandins.诱导多药耐药相关蛋白/谷胱甘肽-S-转移酶-X泵及细胞对抗癌前列腺素的耐药性。

Cytotechnology. 1996;19(3):221-7. doi: 10.1007/BF00744216.

ATP-dependent uptake of natural product cytotoxic drugs by membrane vesicles establishes MRP as a broad specificity transporter.膜囊泡对天然产物细胞毒性药物的ATP依赖性摄取确立了多药耐药相关蛋白作为一种广谱特异性转运蛋白的地位。

Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):6929-34. doi: 10.1073/pnas.93.14.6929.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验