肾细胞癌中的静脉侵犯：对转移行为和生存的影响。
Vein invasion in renal cell carcinoma: impact on metastatic behavior and survival.
作者信息
Ljungberg B, Stenling R, Osterdahl B, Farrelly E, Aberg T, Roos G
机构信息
Department of Urology, Umeå University, Sweden.
出版信息
J Urol. 1995 Nov;154(5):1681-4. doi: 10.1016/s0022-5347(01)66749-1.
PURPOSE
The development of a thrombus extending into the veins is well recognized in renal cell carcinoma. We investigated the hypothesis that vein invasion alone has no adverse impact on survival but is a highly negative factor in other tumors.
MATERIALS AND METHODS
In 200 consecutive patients invasion of the renal vein and vena cava was evaluated and compared with the clinical course.
RESULTS
A total of 26 patients had vena caval and 47 had renal vein invasion. Patients with venous invasion had a significantly shorter survival but no survival difference was demonstrated based on the level of involvement.
CONCLUSIONS
Our study indicates that vein invasion itself seems to be an important prognostic factor in renal cell carcinoma.
目的
肾细胞癌中血栓延伸至静脉的情况已得到充分认识。我们研究了这样一种假说，即单纯的静脉侵犯对生存率没有不利影响，但在其他肿瘤中是一个高度负面的因素。
材料与方法
对连续200例患者的肾静脉和腔静脉侵犯情况进行评估，并与临床病程进行比较。
结果
共有26例患者发生腔静脉侵犯，47例发生肾静脉侵犯。有静脉侵犯的患者生存期明显较短，但根据受累程度未显示出生存差异。
结论
我们的研究表明，静脉侵犯本身似乎是肾细胞癌的一个重要预后因素。
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