Boles Carenini B, Brogliatti B, Boles Carenini A, Sibour G
Clinica Oculistica dell'Universita' di Torino.
Klin Monbl Augenheilkd. 1995 Jul;207(1):37-41.
The vascular factor is becoming increasingly important in the pathogenesis of primary open-angle glaucoma. Ocular hypotonia, which is indubitably a risk factor in the development of glaucoma, cannot be regarded as the sole pathogenic factor. Clinical experience leaves no doubt that some patients tolerate a high IOP for prolonged periods of time without ocular damage. In others, however, severe glaucoma-related lesions result from slight hypertonia or critically low pressure.
The authors analyze the general factors which influence ocular blood flow and increase the deleterious effect of ocular hypertonia, and report results relating to the hemodynamic status of a group of glaucoma patients prior to and after one year of therapy with beta-blockers. The results are analyzed and discussed.
血管因素在原发性开角型青光眼的发病机制中日益重要。眼压过低无疑是青光眼发展的一个危险因素，但不能被视为唯一的致病因素。临床经验表明，一些患者长时间耐受高眼压而无眼部损害。然而，在其他患者中，轻微的眼压升高或临界低压却会导致严重的青光眼相关病变。
作者分析了影响眼血流量并增加高眼压有害作用的一般因素，并报告了一组青光眼患者在接受β受体阻滞剂治疗一年前后的血液动力学状态相关结果。对结果进行了分析和讨论。
