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P170-related multidrug resistance. Enhancement of idarubicin content in leukemic cells with cyclosporin in vivo: a report of two cases.

作者信息

Damiani D, Michieli M, Michelutti A, Pea F, Baraldo M, Fanin R, Russo D, Furlanut M, Baccarani M

出版信息

Leukemia. 1995 Oct;9(10):1792-5.

PMID:7564529
Abstract
摘要

相似文献

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P170-related multidrug resistance. Enhancement of idarubicin content in leukemic cells with cyclosporin in vivo: a report of two cases.P170相关的多药耐药性。环孢素在体内增强白血病细胞中伊达比星含量：两例报告
Leukemia. 1995 Oct;9(10):1792-5.
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P-glycoprotein-mediated drug efflux is a resistance mechanism of chronic myelogenous leukemia cells to treatment with imatinib mesylate.P-糖蛋白介导的药物外排是慢性粒细胞白血病细胞对甲磺酸伊马替尼治疗产生耐药的一种机制。
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Relation among the resistance factor, kinetics of uptake, and kinetics of the P-glycoprotein-mediated efflux of doxorubicin, daunorubicin, 8-(S)-fluoroidarubicin, and idarubicin in multidrug-resistant K562 cells.多药耐药K562细胞中阿霉素、柔红霉素、8-(S)-氟阿霉素和伊达比星的耐药因子、摄取动力学及P-糖蛋白介导的外排动力学之间的关系。
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Overexpression of MDR-related p170 glycoprotein in chronic myeloid leukemia.多药耐药相关p170糖蛋白在慢性髓性白血病中的过表达
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p170-dependent multidrug resistance. Restoring full sensitivity to idarubicin with verapamil and cyclosporin A derivatives.p170 依赖性多药耐药。用维拉帕米和环孢素 A 衍生物恢复对伊达比星的完全敏感性。
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Comparative evaluation of the intracellular accumulation and DNA binding of idarubicin and daunorubicin in sensitive and multidrug-resistant human leukaemia K562 cells.伊达比星和柔红霉素在敏感及多药耐药的人白血病K562细胞中的细胞内蓄积及DNA结合的比较评估
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Cyclosporine diminishes multidrug resistance in K562/ADM cells and improves complete remission in patients with acute myeloid leukemia.环孢素可降低K562/ADM细胞中的多药耐药性，并提高急性髓性白血病患者的完全缓解率。
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