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[塞内加尔人类免疫缺陷病毒感染患者中的五例非伤寒沙门氏菌病]

[Five cases of non-typhoid salmonellosis in patients infected with the human immunodeficiency virus in Senegal].

作者信息

Morel H, Talarmin F, M'Baye P S, Sane M, Ndoye B, Hugard L

机构信息

Service de Médicine, H5bopital Principal, Dakar, Sénégal.

出版信息

Med Trop (Mars). 1995;55(2):135-8.

PMID:7564993
Abstract

Among the opportunistic infections observed during infection with human immunodeficiency virus, recurrent non-typhoid salmonella bacteriemia has not been widely documented in Black Africa. This retrospective study identified 5 cases of non-typhoid salmonellosis in a series of 27 seropositive patients, i.e. 18.5%, hospitalized over a two-year period in an internal medicine department in Senegal. All 27 patients presented general or digestive manifestations and were in the stage of full-blown AIDS. The diagnosis was salmonella septicemia in 60% of cases. The incidence of salmonella is higher in immunocompromised patients than in healthy subjects, particularly in Africa. These infections frequently lead to bacteriemia, have a strong tendency to recur, and are highly indicative of immunodeficiency. Salmonellosis which is curable should be suspected in seropositive African patients presenting general and/or digestive manifestations.

摘要

在人类免疫缺陷病毒感染期间观察到的机会性感染中,复发性非伤寒沙门菌菌血症在非洲黑人中尚未得到广泛记录。这项回顾性研究在塞内加尔一个内科部门两年期间收治的一系列27例血清学阳性患者中,确定了5例非伤寒沙门菌病病例,即18.5%。所有27例患者均有全身或消化系统表现,且处于艾滋病晚期。60%的病例诊断为沙门菌败血症。沙门菌在免疫功能低下患者中的发病率高于健康受试者,在非洲尤其如此。这些感染常导致菌血症,极易复发,是免疫缺陷的高度指征。对于出现全身和/或消化系统表现的血清学阳性非洲患者,应怀疑患有可治愈的沙门菌病。

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