Sparks A E
Department of Urology, University of Iowa Hospitals and Clinics, Iowa City 52242, USA.
Microsurgery. 1995;16(5):345-8. doi: 10.1002/micr.1920160511.
Several methods of gamete microsurgery have been proposed to facilitate the union of the spermatozoon and oocyte in infertile couples. Partial zona dissection, subzonal sperm insertion, and intracytoplasmic sperm insertion are the three techniques currently being used for assisted fertilization in human in vitro fertilization laboratories. Fertilization and pregnancy rates after partial zona dissection and subzonal insertion have been variable and rather low. Recent reports of relatively high fertilization and pregnancy rates achieved after intracytoplasmic sperm insertion have rejuvenated interest in gamete microsurgery. Methods for each procedure are described. Studies which have attempted patient selection for gamete microsurgery are discussed.
为了促进不孕夫妇精子与卵母细胞的结合，人们提出了几种配子显微手术方法。部分透明带切除术、透明带下精子注入术和卵胞浆内单精子注射术是目前人类体外受精实验室用于辅助受精的三种技术。部分透明带切除术和透明带下精子注入术后的受精率和妊娠率各不相同且相当低。最近关于卵胞浆内单精子注射术后获得相对较高受精率和妊娠率的报道，重新唤起了人们对配子显微手术的兴趣。文中描述了每种手术的方法。讨论了尝试对配子显微手术进行患者选择的研究。
