Hanefeld F, Christen H J, Holzbach U, Kruse B, Frahm J, Hänicke W
Kinderklinik, Schwerpunkt Neuropädiatrie, Georg-August-Universität, Göttingen, Germany.
Neuropediatrics. 1995 Apr;26(2):126-7. doi: 10.1055/s-2007-979742.
Combined MRI/MRS studies were performed in 9 girls with Rett syndrome of different ages. NAA, as marker of neuronal tissue, was found to decrease with increasing age. There was no evidence for a defective energy metabolism. The data point towards a probably secondary degenerative process in the pathogenesis of Rett syndrome.
