Kajetán M, Konkoly T M, Jermendy G
Fövárosi Bajcsy-Zsilinszky Kórház III. Belgyógyászati Osztály.
Orv Hetil. 1995 Oct 1;136(40):2161-4.
In order to determine the microbiological characteristics of diabetic foot infection, 60 diabetic patients (21 women, 39 men; age between 43 and 89 years with a duration of diabetes from 0.5 to 37 years) were investigated. Immediately after the hospitalisation specimens from infected foot lesions were taken using Port-A-Cul special transport medium. Aerobic cultures were done in all cases according to conventional methods while anaerobic cultures were carried out when clinical signs indicated to perform it. Out of 60 lesions only 2 proved to be sterile. In the remaining 58 patients a total of 138 isolates were found resulting in an average of 2.3 organisms per lesions. Only aerobic isolates were identified in 45 patients whereas anaerobic species were also found in 12 patients. Only Candida was found in 1 patient while Candida in combination with bacterial strains was observed in 3 patients. In antimicrobial susceptibility testing beta-lactamase-stable antibiotics with broad spectrum, covering enterococcus and anaerobic organisms proved to be most effective. Diabetic foot infections have a polymicrobial nature. Antibiotic treatment of infections should be based on the results of microbiological investigation of diabetic foot.
为了确定糖尿病足感染的微生物学特征，对60例糖尿病患者（21名女性，39名男性；年龄在43至89岁之间，糖尿病病程为0.5至37年）进行了调查。患者入院后，立即使用Port - A - Cul特殊转运培养基采集感染足部病变的标本。所有病例均按照常规方法进行需氧培养，当临床症状提示需要时进行厌氧培养。60处病变中仅有2处培养结果为无菌。在其余58例患者中，共发现138株分离菌，平均每处病变有2.3种微生物。45例患者仅分离出需氧菌，12例患者同时发现了厌氧菌。1例患者仅发现念珠菌，3例患者同时发现念珠菌和细菌菌株。在抗菌药敏试验中，对肠球菌和厌氧菌具有广谱抗菌活性且对β - 内酰胺酶稳定的抗生素最为有效。糖尿病足感染具有多种微生物混合感染的性质。糖尿病足感染的抗生素治疗应基于微生物学调查结果。
