Ginovker A G, Shkliar D G, Kalinicheva E V
Parazitologiia. 1995 Jan-Feb;29(1):19-25.
540 golden hamsters were selected into 3 groups: 1--free from invasion, 2--once infected, 3--repeatedly infected with Opisthorchis felineus. Diurnal activity of peripheral blood composition was investigated in spring, autumn and winter at 3, 7, 11 a.m. and 3, 7, 11 p.m. The dependence of biorhythmical organisation of peripheral blood cell composition upon seasons and the opisthorchis invasion frequency was recovered. The eosinophilia is the marker reaction of opisthorchiasis acute phase and it depend upon the invasion frequency. Seasons and invasion frequency affect on all diurnal rhythm components (mezor, acrophase, amplitude) with most largest drift in spring.
选取540只金黄地鼠分为3组：1组——未受感染，2组——曾感染过，3组——反复感染猫后睾吸虫。于春季、秋季和冬季的上午3点、7点、11点以及下午3点、7点、11点对外周血成分的昼夜活动进行研究。外周血细胞成分的生物节律组织对季节和后睾吸虫感染频率的依赖性得以恢复。嗜酸性粒细胞增多是后睾吸虫病急性期的标志性反应，且它取决于感染频率。季节和感染频率对所有昼夜节律成分（中值、高峰期、振幅）均有影响，其中春季的变化最为显著。
